p38 - Eberhard-Karls-University Tuebingen

Design, synthesis, and biological evaluation of novel Tri- and tetrasubstituted imidazoles as highly potent and specific ATP-mimetic inhibitors of p38 MAP kinase: focus on optimized interactions with the enzyme's surface-exposed front region. Laufer SA, Hauser DR, Domeyer DM, Kinkel K, Liedtke AJ.